1. Use with caution: (1) Alcoholism; (2) Hepatitis; (3) Acute infection; (4) Intestinal inflammation (such as diverticulitis, ulcerative colitis, etc.); (5) Pancreatitis; (6) Digestion Ulcers.
2. The effect of drugs on pregnancy: iron supplementation during pregnancy is most appropriate in the middle and late stages of pregnancy, as the iron intake decreases at this time and the demand increases.
3. After the application of iron, the serum combined transferrin or ferritin increased (easy to lead to missed diagnosis of anemia), and the stool occult blood test was positive (easy to be confused with upper gastrointestinal bleeding).
4. Check or monitor before and after medication and during medication: (1) hemoglobin; (2) reticulocyte count; (3) serum ferritin and serum iron.
5. A clear diagnosis must be made before medication, and the cause of iron deficiency should be found as much as possible.
6. Oral administration of this medicine has mild gastrointestinal reactions. It can be taken immediately after a meal to relieve gastric irritation, but the absorption of the drug will be affected. If the reaction is obvious, reduce the initial oral dose (gradually increase later). During oral iron preparations, it is not advisable to inject iron preparations at the same time to avoid toxic reactions.
7. Usually, the number of reticulocytes in the blood can rise 4~5 days after oral iron, and reach a peak in 7~12 days. Hemoglobin increases significantly in the 4th week of medication, but it usually takes 4~12 weeks to return to normal. After the hemoglobin is normal, the medication must be continued for 2 to 3 months to restore the serum ferritin value to normal.
8. Acute poisoning that occurs when the drug is overdose is more common in children, and a one-time intake of 130 mg of iron can cause death in children. In addition, due to necrotizing gastritis and enteritis, patients may have severe vomiting, diarrhea and abdominal pain, resulting in lower blood pressure, metabolic acidosis, and even coma. After 24 to 48 hours, severe poisoning can further progress to shock, hypovolemia, liver damage, and cardiovascular failure, and the patient may have generalized convulsions.
In the late stage of poisoning, symptoms include clammy skin, cyanosis, lethargy, extreme fatigue and weakness, and tachycardia. Therefore, when acute poisoning is manifested, it should be treated immediately with calcium sodium pentetic acid (pro-pailing) or deferoxamine. After the poisoning is rescued, there may be sequelae such as pyloric or cardiac stenosis, liver damage, or central nervous system disease, which must be properly handled as soon as possible.
Collapse edit this paragraph adverse reactions
This medicine has astringent properties. After oral administration, there are often mild nausea, stomach or abdominal pain, mostly related to the dose. Mild diarrhea or constipation is also common.
